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#PrimaryCare #InternalMedicine #ClinicalPractice To view or add a comment, sign in I have written about HFpEF and obesity twice in the last six weeks SUMMIT (May 15), where tirzepatide reduced CV death and HF events, and the 2025 ACC Scientific Statement (June 4) that placed GLP-1 / GIP therapy in HF management
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Approximately 20-30% of semaglutide users experience minimal weight loss or appetite suppression despite consistent dosing and lifestyle adherence
After 32 weeks of treatment, HbA1c levels and body weight significantly decreased ( 1.38% and 6.03 kg, respectively) and the entity of the reduction was in line with results obtained in the SUSTAIN program [13, 19, 20], where HbA1c was reduced from 1.1 to 1.5% with semaglutide 0.5 mg and from 1.4 to 1.8% with semaglutide 1 mg