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[PMC free article: PMC435850] [PubMed: 16694075] 389

It's a receptor ligand with limited binding sites, a saturation ceiling, and insulin receptor cross-reactivity that produces hypoglycemia when dosed without regard to timing or metabolic context

A high content drug screen identifies idelalisib as a selective inducer of apoptosis in senescent cells

L.P., D.A.H., J.M.D

An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand Clinical Observations