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The majority of the sample were women, range 4150 years old, Fitzpatrick IV skin type, had a family history of melasma, with daily UV exposure 36 hrs per day, dentofacial melasma pattern, mixed melasma type, and mild category of melasma based on MASI index (Table 1)

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Its distinctive inactive-to-active conversion within the tumor microenvironment augments metabolic targeting and selectivity, which underscores its potential as a groundbreaking therapeutic strategy [186, 187]

In addition, semaglutide had the greatest risk of nausea, diarrhea, vomiting, constipation, and pancreatitis, while liraglutide had the greatest risk when it came to upper abdominal pain