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Combination therapies may use drugs already available for other indications

In studies, both Wegovy and metformin have been shown to have protective effects on the heart, especially in people who have Type 2 diabetes or a history of heart disease

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Trump Administration Pushed for Cheaper Weight-Loss Drug Prices The Trump administration announced plans in November 2025 to reduce the cost of GLP-1 medications for Americans after reaching a deal with drug manufacturers Eli Lilly and Novo Nordisk

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