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More specifically, the ARC nucleus of the hypothalamus has been highlighted as one of the main sites mediating this action as chemical lesion of the ARC in rats ablates the anorectic action of GLP-1 (Tang-Christensen et al., 1998)

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they are not standardized and are not the same as controlled clinical trial regimens

Clinically, skin aging is manifested by visible changes such as wrinkles, laxity, and hyperpigmentation [34]