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Pregnancy as a window to future health: excessive gestational weight gain and obesity

These studies, conducted in cell cultures and animal models, were instrumental in demonstrating the potential for synergistic metabolic effects beyond what could be achieved with single-agonist compounds

Research published in Cell Reports Medicine in 2026 concluded directly: weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function

Mori-Akiyama Y, van den Born M, van Es JH, Hamilton SR, Adams HP, Zhang J, et al

Renal function : While most GLP-1 receptor agonists do not require dose adjustment for mild to moderate renal impairment, your kidney function influences medication selection and monitoring frequency