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doi:10.1523/JNEUROSCI.2063-23.2024 26

In the long run, the sustained improvement of liver function markers is closely related to a reduced risk of disease progression, including cirrhosis and HCC [45]

GSH is present in tissues at concentrations ranging from 1 to 10 mM and, on account of its ability to donate reducing equivalents, it is essential for both direct (chemical) and enzymatic neutralization of toxic reactive species and, in particular, for cellular defense towards oxidants [1]

Under physiological conditions, laminar blood flow keeps the vascular wall in a quiescent state, with a predominance of NO signaling, which inhibits inflammation, cellular proliferation, and thrombosis [55, 56]