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Evidence supporting combined therapy is emerging but remains limited as a recent meta-analysis of randomized controlled trials reported lower risk of HF hospitalization with concomitant SGLT2 inhibitor and GLP-1 receptor agonist therapy compared with monotherapy or standard care [24]

There is a wealth of evidence that suggests protein supplementation is a useful tool to gain muscle (when in combination with a strength/resistance-based workout routine)

However, GLP-1 therapy offers a less invasive, lower-risk alternative with potentially similar results

2) By comparison, semaglutide (Ozempic) in clinical trials resulted in more weight loss overall relative to the weight loss data seen with berberine

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