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JCI Insight 5 , e134920 (2020)

Because retatrutide is not yet licensed in the UK, individuals who are participating in clinical trials or who have accessed the drug through other means should maintain open communication with a qualified healthcare professional

Some users explore combining tirzepatide with other compounds

Variants in GLP1R, GIPR, FTO, and MC4R can support a more informed conversation with your provider about whether 0.25mg is likely to be sufficient or whether earlier dose escalation might be appropriate for your unique physiology

Patients should be advised to monitor for these symptoms after each dose of a GLP-1 agonist