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Furthermore, a dual luciferase reporter system assay demonstrated that the luciferase activity of GGCT-3 untranslated region (UTR) (wild-type) decreased after transfection with miR-29b-3p mimics, while the luciferase activity of GGCT-3 mUTR (mut) did not show significant changes in MHCC97H and LNCaP cells (Fig

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Moreover, in facing various pathological challenges, the mammalian heart, which possesses high levels of mitochondria and weak antioxidant capacity, is susceptible to oxidant production and oxidative damage