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They were absolutely three alarming complications, but then we have enough evidence on all three to believe that we really do not have increased risk of any of them. However, one organ that has been affected by GLP-1 agonists in randomized trials is the gallbladder (7)

Water Supplementation Enhances the Effect of High-Fiber Diet on Stool Frequency and Laxative Consumption in Adult Patients with Functional Constipation. Hepatogastroenterology , vol

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Semaglutide is a medication approved by the FDA