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Psychiatry 67 (Suppl

This concept of microdosing GLP-1s gained traction due to obesity drug shortages shortly after these new, highly effective medications were approved in 2021 and 2022

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These findings support the use of Retatrutide as a mechanistic probe for studying how multiple receptor systems interact to regulate metabolic pathway activity and cellular energy balance in controlled experimental models

The UACR reductions were dose-dependent, larger at higher doses, and sustained through 72 weeks of treatment without any detrimental effect on estimated glomerular filtration rate