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Once a patient is on a maintenance dose, their B12 levels are generally stable, and a single days difference is unlikely to have a clinical impact

Deficiency is widespread, with peer-reviewed research describing it as a global health concern affecting populations across all age groups and geographies (Cashman et al., American Journal of Clinical Nutrition , 2016

Other GLP-1 and dual-agonist agents, including tirzepatide, are also in wide use, though not every GLP-1 on the market carries an FDA weight loss indication

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