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In another adjuvant breast cancer trial (the ECOG-1178 trial), hot flashes were reported in 19% of women who received 2 years of tamoxifen compared with 8% of women who received placebo following a mastectomy

LUPKIN: That "have to have" and Eli Lilly and Novo Nordisk's failure to predict it, that's what has turned our whole system upside down and given us all a glimpse of a messier market for drugs, where the big drug companies don't hold all the cards because the competition doesn't have to wait, and customers can get what they want when they want, but at their own risk

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