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Poor blood sugar control and obesity are closely linked in a cycle where each can contribute to the other: high blood sugar caused by insulin resistance results in excess production of insulin, which in turn encourages the body to store fat, while obesity worsens insulin resistance

Akhlaghi M

Patients with IBS-D (diarrhoea-predominant) may be particularly concerned about GLP-1-induced diarrhoea, whilst those with IBS-C (constipation-predominant) might experience either improvement or worsening depending on individual response

HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription

Others may achieve stable response with minimal clinic contact, potentially favoring a lower-cost compounded model