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If you notice the stopper surface deteriorating or if the vial no longer holds vacuum (you don't hear a slight hiss when first puncturing), replace the vial or transfer contents to a fresh sealed container

Immunogenicity associated with metreleptin treatment in patients with obesity or lipodystrophy

Bursitis is a condition that causes pain and swelling in the small, fluid-filled sacs called bursae that cushion your joints