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Studies have shown that in such rebound cases, much of the weight loss is in lean muscle mass, which is less likely to be restored without some form of weight-bearing exercise

This limits the applicability of our results to not only the younger female patients, but also to individuals who may be overweight, obese, or have renal disease, diabetes, or psychiatric disorders but no history of CVD

A serum B12 level test and, ideally, a methylmalonic acid (MMA) test should precede any B12 injection recommendation

doi: 10.1371/journal.pone.0072215 550 Clemente-SurezVJBustamante-SanchezMielgo-AyusoJMartnez-GuardadoIMartn-RodrguezATornero-AguileraJF

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