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Patients who follow the program may experience gradual weight reduction, often in the range of 1 to 2 pounds per week, depending on individual factors

1) A set of well identified inflammatory biomarkers (IL-6, TNF-, IL-1, IFN-, neutrophil and NET biomarkers) 2) Additional biomarkers including the awakening cortisol response, zonulin, tryptophan, kynurenine 3) Key quantified questionnaire-based symptoms (fatigue, ability to concentrate and to memorize) and number of symptoms 4) Functional tests including HRV, VO 2max , orthostatic intolerance and cognitive tests

The amino acid makeup of IDPs/IDRs is fundamentally different from that of ordered proteins, defining their inability to form stable structure (Dunker et al., 1998

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We developed a high-throughput screening assay for GST P1-1 and screened 5830 compounds