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Originally discovered in human gastric juice, this peptide acts as a foundational signaling molecule for mucosal protection and internal balance (homeostasis)

[Journal of the Brazilian Chemical Society, 2010, vol

Nesbitt, Andrew, Gianluca Fossati, Marianne Bergin, Paul Stephens, Sue Stephens, Roly Foulkes, Derek Brown, Martyn Robinson, and Tim Bourne

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Nuclear factor-kappa B (NF-B) is a transcription factor that binds DNA and induces the transcription of the COX-2 gene, other pro-inflammatory genes, as well as genes involved in cell proliferation, adhesion, survival, and differentiation