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The lack of evidence surrounding yellowing of the lens tissue with age (or UV exposure) in these larger animals, however, means that while they are useful for understanding potential changes to proteins resulting from photooxidation and photosensitisation, they lack a key characteristic of human UV cataract
The main negative regulator of NF-B activity is zinc finger protein (A20), which is known as a cell protector against TNF--induced NF-B toxicity, decreasing its level, along with IL-1
Stanley JA, Drost DJ, Williamson PC, Thompson RT
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