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In addition to profoundly compromising quality of life and daily functioning, this disorder contributes to the pathogenesis of numerous chronic diseasesincluding hypertension, coronary artery disease, stroke, diabetes, and cognitive impairmentand has been correlated with elevated all-cause mortality risk (46)

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About this article Cite this article Ono, Y., Shinohara, K., Nakashima, H

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The decrease in hyperglycaemia after administration of GLP-1 or GLP-1MK-801 was not associated with changes in plasma insulin levels (Extended Data Fig