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Supernatants were removed and 100 L of DMSO was added to each well to solubilize the formazan crystals

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

Hcy self-oxidation generates ROS, disrupts redox homeostasis, and induces neuronal apoptosis via upregulation of Bax protein expression and activation of the caspase-3 pathway ( MMA further contributes to oxidative stress by impairing the mitochondrial respiratory chain complexes and energy metabolism

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Using a continuous assay, we determined K M s of recombinant Cr GPDH as 45 3 M for NADH and 820 127 M for DHAP, while k cat s were 147 10 and 248 36 s 1 , respectively ( Figure 2e-f , Table 1 )