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Lyophilised peptides tolerate short-term ambient exposure better than reconstituted solutions, but anything beyond 72 hours at 25C or 24 hours above 30C likely caused measurable degradation

The brain is particularly susceptible to oxidative stress given its limited antioxidant enzymatic capacity to counteract reactive oxygen species production (Ferreira et al., 2015)

The multiple-reaction-monitoring (MRM) spectra were obtained with a QTRAP 5500 mass spectrometer (AB SCIEX) equipped with an ESI source

Conversely, in pro-resolving mouse macrophages, arginine is converted by arginase 1 (Arg1) into ornithine, a precursor of polyamines (Rath et al., 2014)

Whilst vitamin B12 toxicity is exceptionally rare due to its water-soluble nature, very high levelsparticularly from mega-dose supplements or frequent injectionshave been associated with certain adverse effects, most notably skin reactions