BJP-IVb prevents PD by inhibiting iron regulatory protein (IRP2) from iron overload-mediated ferroptosis in dopaminergic neurons, as demonstrated by diminished lipid peroxidation and reduced iron content
Dark green vegetables (e.g., spinach, broccoli, Brussels sprouts, and romaine lettuce), cereals (especially whole grains), fruits (e.g., oranges, papaya, and avocado), and legumes (e.g., chickpea, soybean, and lentil) are the major sources 1,13,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89
Sun L, Zhang Y, Yang B, Sun S, Zhang P, Luo Z, et al
Pay close attention to your body's signals and speak with your doctor about any concerns that you may have
However, direct hormone replacement often bypasses the bodys natural endocrine feedback loops, leading to potential metabolic complications, receptor downregulation, and significant costs that limit long-term clinical utility