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Through its multi-target mechanism of action (anti-inflammation, mucosal repair, angiogenesis), it provides a new option for patients who are ineffective or intolerant to traditional treatments

Pegaptanib includes a 40 kDa polyethylene glycol (PEG) unit at the 5 end to aid in renal clearance, along with a 3-3-linked deoxythymidine residue to enhance resistance to nuclease degradation (106)

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Originally isolated from human gastric juice, this 15-amino acid compound has been studied in preclinical animal models across multiple physiological systems.*1,9,10