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Xiao Z, Cilz NI, Kurada L et al (2014) Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimers disease model
Understanding which one does what helps explain why retatrutide's diarrhea profile differs from simpler drugs like semaglutide
10.1093/ibd/izz046 47 ChenS
More work is needed to figure out which patients might benefit, how these drugs might be combined with other therapies, and whether they are safe over the long term
Multiple devices leave patients confused some may not prime the pen correctly, others may dial the wrong dose, and some may struggle with changing the cartridges or needles
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