They should not be used by patients with a history of pancreatic issues, certain liver conditions, thyroid cancer, or pancreatic cancer, as use of the drug can exacerbate these conditions, Tavakol says
She said playing a role in supporting weight loss journeys for such a long time is a "huge differentiation and a really strong foundation to build upon." Having a more long-term view of the weight management space also plays into how the company is thinking about the role of GLP-1s in the broader patient journey, she said
For individuals requiring supplementation due to confirmed deficiency or malabsorption, therapeutic doses vary considerably depending on the underlying cause: Dietary deficiency : 50150 micrograms daily orally, or cyanocobalamin tablets as prescribed Pernicious anaemia : Initially hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks, then maintenance injections every two to three months [3] Neurological involvement : More intensive regimens may be required, with hydroxocobalamin injections on alternate days until symptom improvement [3] NICE guidance emphasises that supplementation should be evidence-based rather than speculative
MM: Conceptualization, Writing review & editing, Supervision
Black Cohosh has been associated with rare liver-related concerns in published case reports