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Senescent vascular smooth muscle cells drive inflammation through an interleukin-1-dependent senescence-associated secretory phenotype

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Reference Mehler, Yager and Solomon15,Reference Gibson, Workman and Mehler16 Our patient lost approximately 20 kg in 6 months, similar to the patient of Guerdjikova et al, Reference Guerdjikova, Ward, Ontiveros and McElroy27 which was more weight than the average weight loss reported in clinical trials of semaglutide