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SGLT2 inhibitors therefore do not merely lower glycemia, but introduce a parallel energetic pathway that may buffer against progressive metabolic failure in vulnerable neural circuits

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Mol Cell Biol 20:18681876 Vernon AC, Zbarsky V, Datla KP, Croucher MJ, Dexter DT (2007) Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo

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