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By genotyping about 200 patients with prolactinomas and controls for common DRD2 polymorphisms, DA-resistance has been correlated only to a common polymorphism, a synonymous cytosine to thymine transition at position 957, a change that has been associated with susceptibility to migraine and schizophrenia, and that might alter the predicted mRNA folding, leading to a decrease in mRNA stability and translation (38)

Aging 34 , 15811588 (2013)

ENVEJECIMIENTO DEL SUEO Y DECLIVE DEL SUEO RELACIONADO CON LA EDAD El sueo delta disminuye progresivamente con la edad, un sello distintivo del envejecimiento y un contribuyente al declive cognitivo relacionado con la edad y al deterioro de la salud

In addition, the following observations suggested the close relationship between TLRs and adaptive immunity or innate immunity