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For example, in a United States retrospective study [20] , it was found that women have a higher risk of adverse outcomes than men in cases of acetaminophen-induced acute liver injury

Signs and symptoms of Dercum disease include chronic pain, fatigue, brain fog, insomnia, cardiac arrhythmia most often tachycardia (palpitations), gastrointestinal distress often similar to irritable bowel syndrome, muscle weakness, tremor or jerking of muscles (myoclonus), joint pains, insulin resistance and diabetes, hypothyroidism, and other autoimmune disorders (219)

Owing to their distinct biochemical mechanisms that suppress lipid peroxidation and reduce ROS production, these compounds have been investigated in clinical studies to assess the therapeutic value of their antioxidant properties (Table 1)

SRCP formulations have better compatibility but caution is still advised

This is mechanism evidence, not outcome evidence