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if suspected or confirmed, discontinue semaglutide and do not restart [1] [3] Monitoring for gallbladder disease, particularly in patients with rapid weight loss Risk of diabetic retinopathy complications in patients with type 2 diabetes Potential for acute kidney injury, especially with dehydration from gastrointestinal side effects Rare but serious hypersensitivity reactions including anaphylaxis Contraindication in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 [1] [3] Not recommended during pregnancy or breastfeeding

Clinicians working within the NHS are not in a position to prescribe or recommend retatrutide to patients

This topic should be handled carefully and responsibly

Handgrip strength improved by approximately 4.5 kg at 12 months

Some researchers find they sleep more deeply but feel groggy upon waking