Indicatively, BPC 157 induced a NO-release of its own [49,67,68] and therefore counteracted both NO-synthase (NOS) inhibition (i.e., N(G) nitro-L-arginine methylester (L-NAME) hypertension and pro-thrombotic effects) and NO overstimulation (L-arginine hypotension and anti-thrombotic, pro-bleeding effects) [49,67,69]

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The thiol side chain of cysteine often participates in enzymatic reactions such as a nuecleophile (a chemical species that donates an electron pair to an electrophile to form a chemical bond in relation to a reaction)
This approach helps minimize side effects while allowing the body to adapt to the treatment
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