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At a central level, the anorectic effect of glucagon is mediated by a hypothalamic pathway involving a PKA/Ca 2+ calmodulin-dependent protein kinase kinase (CaMKK)/AMP-activated protein kinase (AMPK)-dependent mechanism [56]

Delton Family Distinguished Professor in Organic Chemistry, and Joshua Munger, professor in the Department of Biochemistry and Biophysics and an expert in cancer cell metabolismare exploring ways to refine potential drugs that could inhibit this process and improve outcomes for patients