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Osteoclasts are derived from haematopoietic stem cells (HSCs), specifically from the monocyte/macrophage lineage ( Figure 1 )

Available non-GLP-1 options include NAD+ injections, sermorelin, and MIC-B12

[11] Weight changes in the first few weeks are typically modest, with most patients losing 12 kg during the initial month

We would like to thank Susanne Pors, Senior Scientist, Histology, Gubra who the MASLD activity score, and the team at Gubra who conducted the MASLD assessment in Gubra-Amylin NASH (GAN) DIO-MASH mice