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In this combined analysis, we observe that the degree of BMI loss depends strongly on sex, drug type, time on treatment and drug dosage, consistent with previous reports 11 , and has a relatively weak dependence on pre-treatment BMI (with higher starting BMI associated with greater BMI loss)

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Additionally, research has shown that as the number of components of Metabolic Syndrome (MetS) increases, there is a corresponding increase in both plasma PAI-1 levels and activity

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A patient may need a different dosage form, a strength that is not commercially available, or a formulation that omits an ingredient to which the patient is allergic