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During I/R injury, the intestinal barrier becomes weakened, allowing microbial translocation, endotoxins, and inflammatory mediators such as cytokines to enter the bloodstream

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Optimal vitamin K2 intake is critical to avoid the calcium plaque buildup of atherosclerosis, thus keeping the risk and rate of calcification as low as possible

As the main antioxidant enzyme in plasma, GPx3 is the only extracellular enzyme in the GPx family that reduces ROS products during normal metabolism or oxidative damage [15]