But the most important part is the language it uses to cover things it doesn't name
It occupies a gray-area status similar to many research peptides
Since polyphenols can act as PAINS in biochemical assays (autofluorescence, redox cycling, aggregation, metal chelation), in-vitro hits without orthogonal validation were downgraded
Relevant reading includes the BPC-157 research overview, the angiogenesis and nitric-oxide signaling discussion, the scratch-wound migration assay methodology, and in-vitro angiogenesis assay models
These included reductions in functional and cardiovascular age, greater exercise tolerance, and notably lower mortality: treated individuals had 28% fewer deaths overall, about half the cardiovascular mortality, and reduced incidence of heart failure & respiratory disease compared to controls