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Common Side Effects Mild nausea Bloating Changes in bowel habits such as constipation or diarrhea Reduced appetite Headaches Fatigue Controlling mild side effects is key to maintaining patient adherence

Parental exposure to benzo(a)pyrene in the peripubertal period impacts reproductive aspects of the F1 generation in rats

A pooled analysis of the 563 patients who were randomly assigned to receive dabrafenib plus trametinib in the COMBI-d (double-blinded) and COMBI-v (open label) trials (described above) provides estimated 5-year outcomes.[31] After the study, 53% of patients received subsequent treatment

Self-reported community sources describe injection-site reactions and fluid retention scaling with daily dose

Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by CHK1 inhibition