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Factors affecting efficacy include existing endothelial function, individual amino acid metabolism, comorbidities (diabetes, metabolic syndrome, prior cardiovascular events), and - critically - dose

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For instance, the fruit product dried prunes (138), conventionally categorized as a dietary supplement, has been shown to restore bone loss in OVX mice, as further studies have attributed this effect to polyphenols and carbohydrates, which are more explicitly identified as prebiotics

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In the ICU, he receives IVIG, methylprednisolone, and low-dose aspirin as therapy for an ultimate diagnosis of MIS-C