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Survodutide, a glucagon/GLP-1 dual agonist, met its primary endpoint of histological improvement in MASH at 48 weeks and also demonstrated a statistically significant improvement in fibrosis, a secondary endpoint

For short-term storage, keep peptides at 4C, but use them promptly to avoid potential degradation

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Further, a growing body of evidence suggests that increased insulin, in addition to IGF1 and IGF2 levels critically influence tumor initiation and progression in IR patients

Ethics statement The animal study was reviewed and approved by Xiangya Hospital Central South University