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Description

Neurologic manifestations will not be prevented with folic acid, and if not treated with vitamin B 12, irreversible damage will result

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Specifically, 8 of the 11 sites are fully identical over the 10 residues spanning the P5 to P5 positions, and only two of the 11 cleavage sites have more than a single amino acid difference within the 10 residue span (Figure S1)

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