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Orbitrap-Fusion mass spectrometer (Thermo Finnigan, San Jose, CA) was used for mass spectrometry analysis

An underactive thyroid slows down metabolic processes, leading to fatigue, weight gain, cold intolerance, and sluggishness. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDKD) reports that hypothyroidism is more common than hyperthyroidism and is often linked to the autoimmune disorder Hashimotos disease

Perales-Clemente, E., Folmes, C

Clin Pharmacokinet 51:553572 Ricciolini R, Scalibastri M, Kelleher JK, Carminati P, Calvani M, Arduini A (1998) Role of acetyl-l-carnitine in rat brain lipogenesis: implications for polyunsaturated fatty acid biosynthesis