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Orally administered semaglutide versus GLP-1 RAs in patients with type 2 diabetes previously receiving 12 oral antidiabetics: systematic review and network meta-analysis

During a drug holiday specifically, sleep quality becomes even more important because you have lost the medication-driven appetite suppression that previously compensated for suboptimal sleep habits

10.1111/dom.14089 10 BornerT.TinsleyI

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Consequently, diabetic subjects treated with GLP-1 receptor agonists often experience weight loss as opposed to the weight gain commonly induced with other treatment agents