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By contrast, HA + GSH-C4 did not significantly alter IL-6 or IL-10, whereas the HA-only preparation at 50 L induced a modest reduction in both cytokines during H 2 O 2 exposure (p 0.006)

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Otero-Albiol, D

Transcription factors regulation in human peripheral white blood cells during hypobaric hypoxia exposure: an in-vivo experimental study

The mechanistic core of the finding was that Dihexa activated the PI3K/AKT signaling pathway in the brains of the APP/PS1 mice, and that the PI3K inhibitor wortmannin reversed Dihexas anti-inflammatory and anti-apoptotic effects [5]