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It works by helping the kidneys get rid of glucose from your bloodstream

The pharmacokinetic data, the 120-hour half-life, the 8-to-72-hour peak absorption window, the 1.6-fold steady-state accumulation, all comes from studies of these pharmaceutical formulations

That is not unusual for smaller companies, but it does mean the BBB rating is based on a relatively short track record

These are protein-based biological products that can degrade when exposed to temperatures outside their recommended storage range

And as you and I have discussed before, if you had a drug that you were giving to a patient that slowed kidney disease progression but increased the risk of death, there'd be little value to that