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Se han establecido dos fases para la suplementacin: una fase de carga de 20 g de CM por da o 0.3 g de CM/kg de peso corporal/ por da dividida en 4 tomas de 5 g cada una, seguida de una fase de mantenimiento 3-5 g de CM al da

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133,134 Diagnostic criteria for HPS in patients with cirrhosis include PaO 2 6% suggests HPS as the major contributor to hypoxemia