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355,356 The BBB not only allows highly selective permeability of substances entering and exiting through specialized structures (seal off adjacent BECs) but also dynamically regulates cerebral blood flow through the process of neurovascular coupling, maintaining homeostasis and neuronal function in the CNS

[Abstract] J Inflamm (Lond)

Someone that's heavier might need a needle that's slightly longer

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U., and Kim, G