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Foundational NNMT Discoveries The foundational research establishing NNMT as a metabolic regulator and potential therapeutic target came from studies by Daniel Kraus and colleagues published in Nature in 2014, which demonstrated that NNMT expression is dramatically upregulated in adipose tissue of obese humans and diet-induced obese mice, and that genetic knockdown of NNMT in mice protected against diet-induced obesity and improved metabolic parameters

Familial PC, hereditary pancreatitis, and several hereditary tumor predisposition syndromes are examples of inherited risk factors [67]

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It has skin conditioning properties due to its abundance of antioxidants like Chlorogenic Acid, Caffeic Acid, and Nasunin