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The two most popular options, semaglutide and tirzepatide , have different mechanisms and produce somewhat different transformation patterns

SGLT2 Inhibitors There are several cardiovascular outcome trials testing the efficacy of SGLT2-i as listed in Table 3 and Table 4

These medications not only help to improve glycemic control but also have been shown to have cardiovascular benefits in some patients

The recommended injection sites include the abdomen, thigh, and upper arm, rotating them with each dose to prevent pain, bruising, and skin thickening

Acute, severe, or persistent pain, or any pain with fever, vomiting or jaundice, needs urgent review